{"id":251510,"date":"2025-03-04T14:26:08","date_gmt":"2025-03-04T14:26:08","guid":{"rendered":"https:\/\/news.talkwithrattan.com\/index.php\/2025\/03\/04\/james-harrison-whose-antibodies-helped-millions-dies-at-88\/"},"modified":"2025-03-04T14:26:08","modified_gmt":"2025-03-04T14:26:08","slug":"james-harrison-whose-antibodies-helped-millions-dies-at-88","status":"publish","type":"post","link":"https:\/\/news.talkwithrattan.com\/index.php\/2025\/03\/04\/james-harrison-whose-antibodies-helped-millions-dies-at-88\/","title":{"rendered":"James Harrison, Whose Antibodies Helped Millions, Dies at 88"},"content":{"rendered":"<div style=\"text-align:center\"><img decoding=\"async\" src=\"https:\/\/i3.wp.com\/static01.nyt.com\/images\/2025\/03\/03\/multimedia\/03Harrison--03-qltf\/03Harrison--03-qltf-facebookJumbo.jpg?ssl=1\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"James Harrison, Whose Antibodies Helped Millions, Dies at 88\" title=\"James Harrison, Whose Antibodies Helped Millions, Dies at 88\" \/><\/div><p> <br \/>\n<\/p>\n<div data-testid=\"companionColumn-0\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">James Harrison did not much care for needles. Whenever he donated plasma, he would look away as the tip went into his arm.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">But Mr. Harrison, an Australian who died last month at 88, was one of the most prolific donors in history, extending his arm 1,173 times. <a class=\"css-yywogo\" href=\"https:\/\/www.nytimes.com\/2018\/05\/14\/world\/australia\/australian-blood-donor.html\" title=\"\">He may have also been one of the most important<\/a>: Scientists used a rare antibody in his plasma to make a medication that helped protect an estimated 2.4 million babies in Australia from possible disease or death, medical experts say.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cHe just kept going, and going, and going,\u201d his grandson Jarrod Mellowship, 32, said in an interview on Monday. \u201cHe didn\u2019t feel like he had to do it. He just wanted to do it.\u201d<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Mr. Harrison \u2014 who was affectionately known as \u201cThe Man with the Golden Arm\u201d \u2014 died in his sleep at age 88 on Feb. 17, at a nursing home about an hour\u2019s drive north of his regular donation center in Sydney, Mr. Mellowship said.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-1\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">Mr. Harrison\u2019s plasma contained a rare antibody, anti-D. Scientists used it to make a medication for pregnant mothers whose immune systems could attack their fetuses\u2019 red blood cells, <a class=\"css-yywogo\" href=\"https:\/\/www.lifeblood.com.au\/news-and-stories\/media-centre\/media-releases-and-statements\/vale-james-harrison-oam\" title=\"\" rel=\"noopener noreferrer\" target=\"_blank\">according to Australian Red Cross Lifeblood<\/a>.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">It helps protect against problems that can occur when babies and mothers have different blood types, most often if the fetus is \u201cpositive\u201d and the mother is \u201cnegative,\u201d <a class=\"css-yywogo\" href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/erythroblastosis-fetalis\" title=\"\" rel=\"noopener noreferrer\" target=\"_blank\">according to the Cleveland Clinic<\/a>. (The positive and negative signs are called <a class=\"css-yywogo\" href=\"https:\/\/www.redcrossblood.org\/local-homepage\/news\/article\/what-is-the-rh-factor--why-is-it-important-.html#:~:text=The%20Rh%20factor%20is%20one,to%20categorize%20a%20blood%20donation\" title=\"\" rel=\"noopener noreferrer\" target=\"_blank\">the Rhesus factor, or Rh factor<\/a>.)<\/p>\n<p class=\"css-at9mc1 evys1bk0\">In such cases, a mother\u2019s immune system might react to the fetus as if it were a foreign threat. That can lead babies to develop a dangerous and potentially fatal condition, hemolytic disease of the fetus and newborn, which can cause <a class=\"css-yywogo\" href=\"https:\/\/www.nationwidechildrens.org\/conditions\/hemolytic-disease-of-the-fetus-and-newborn-hdfn\" title=\"\" rel=\"noopener noreferrer\" target=\"_blank\">anemia and jaundice<\/a>.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The condition is uncommon: Only about 276 out of 100,000 live births have complications related to this type of blood incompatibility, the Cleveland Clinic said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">But doctors cannot predict whether such an incompatibility will lead to serious problems. So, in Australia, the practice is to offer the medication to all pregnant women with negative antibodies as a preventative measure, <a class=\"css-yywogo\" href=\"https:\/\/www.lifeblood.com.au\/blood\/learn-about-blood\/plasma\/anti-D\" title=\"\" rel=\"noopener noreferrer\" target=\"_blank\">according to Lifeblood<\/a>.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-2\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">In Australia, that\u2019s about 17 percent of the population, or about 45,000 women a year. In the United States, it\u2019s about 15 percent, according to the Cleveland Clinic.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">In Australia, scientists from the Walter and Eliza Hall Institute of Medical Research in Melbourne are working to create a synthetic version of the drug using what some have called \u201cJames in a Jar,\u201d an <a class=\"css-yywogo\" href=\"https:\/\/www.lifeblood.com.au\/news-and-stories\/trending-research\/understanding-the-anti-d-immune-response\" title=\"\" rel=\"noopener noreferrer\" target=\"_blank\">antibody that can be made in a lab<\/a>.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">But for now, human donors are essential: The anti-D shots are made with donated plasma, and Mr. Harrison was one of about 200 donors among the 27 million people in Australia, Lifeblood said.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cIt wasn\u2019t one big heroic act,\u201d Ms. Falkenmire said in an interview as she reflected on Mr. Harrison\u2019s 64 years of donations, from 1954 to 2018. \u201cIt was just a lifetime of being there and doing these small acts of good bit by bit.\u201d<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-3\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">Mr. Harrison sometimes met some of the women he helped, although most were strangers.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-4\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">But two he knew well indeed. His daughter, Tracey Mellowship, received an anti-D injection made with Mr. Harrison\u2019s plasma. So did his granddaughter-in-law, Rebecca Mellowship, who is married to Mr. Mellowship.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cIt was special that I received dad\u2019s anti-D,\u201d Tracey Mellowship, 58, wrote in an email.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">But his rare antibodies were only part of the puzzle. Mr. Harrison\u2019s commitment was key. He donated about every two weeks from age 18 to age 81, first his blood and then his plasma.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Vacations did not stop him: He would stop in clinics across Australia when he and his wife, Barbara Harrison, traveled in their camper van. She was a prolific blood donor, too.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Neither did old age: He rode the train for more than an hour each way to get from his home outside Sydney to his regular donation center.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">And he never missed an appointment, said Ms. Falkenmire, the Lifeblood spokeswoman, who talked to him during donations.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-5\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">Partially, she said, they just enjoyed chatting. But he also welcomed the distraction: \u201cHe was petrified of needles,\u201d she said. \u201cHe hated them.\u201d<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Mr. Harrison knew the importance of his work firsthand. At 14, he needed a lot of blood transfusions during a major lung surgery. The experience inspired him to donate and encourage others to donate, too.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cHe would walk up to people who were donating for the first time and congratulate them, and tell them they were important and special,\u201d Ms. Falkenmire said, \u201cwithout revealing anything about his own donations.\u201d<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-6\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">James Christopher Harrison was born on Dec. 27, 1936, in Junee, a small town in New South Wales, to Peggy and Reginald Harrison.<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<div data-testid=\"companionColumn-7\">\n<div class=\"css-53u6y8\">\n<p class=\"css-at9mc1 evys1bk0\">After he recovered from lung surgery, Mr. Harrison met his wife, the former Barbara Lindbeck, when he was a teenager. She was a teacher who died in 2005, Ms. Falkenmire said. He worked as a clerk in the regional railway authority and <a class=\"css-yywogo\" href=\"https:\/\/www.lifeblood.com.au\/news-and-stories\/stories\/james-harrison\" title=\"\" rel=\"noopener noreferrer\" target=\"_blank\">received the Medal of the Order of Australia in 1999<\/a> for his donations.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Mr. Harrison is survived by his daughter, Tracey, and her husband, Andrew Mellowship; his grandsons Scott and Jarrod Mellowship; and Jarrod\u2019s family: Rebecca, his wife, and their four children.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">And also, maybe, 2.4 million babies \u2014 which Mr. Harrison never quite knew how to comprehend.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cSaving one baby is good,\u201d he said, after his final donation in 2018. \u201cSaving two million is hard to get your head around, but if they claim that\u2019s what it is, I\u2019m glad to have done it.\u201d<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Mr. Harrison\u2019s wish, he liked to say, was that people would keep donating. Maybe even more than he did, Mr. Mellowship said: \u201cBecause then it means the world\u2019s going in the right place.\u201d<\/p>\n<\/div>\n<aside class=\"css-ew4tgv\" aria-label=\"companion column\"\/><\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.nytimes.com\/2025\/03\/04\/obituaries\/james-harrison-dead-blood.html\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>James Harrison did not much care for needles. Whenever he donated plasma, he would look away as the tip went into his arm. But Mr. Harrison, an Australian who died last month at 88, was one of the most prolific donors in history, extending his arm 1,173 times. He may have also been one of [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":251511,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","fifu_image_url":"https:\/\/static01.nyt.com\/images\/2025\/03\/03\/multimedia\/03Harrison--03-qltf\/03Harrison--03-qltf-facebookJumbo.jpg","fifu_image_alt":"","footnotes":""},"categories":[1],"tags":[56952,1386,194781,194780,163460,16,133906,3227,3594,194782,6330],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/posts\/251510"}],"collection":[{"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/comments?post=251510"}],"version-history":[{"count":1,"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/posts\/251510\/revisions"}],"predecessor-version":[{"id":251512,"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/posts\/251510\/revisions\/251512"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/media\/251511"}],"wp:attachment":[{"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/media?parent=251510"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/categories?post=251510"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/news.talkwithrattan.com\/index.php\/wp-json\/wp\/v2\/tags?post=251510"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}