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The blood holds clues to understanding long COVID

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The blood holds clues to understanding long COVID

T. Thaweethai et alDevelopment of a definition of postacute sequelae of SARS-CoV-2 infectionJAMA. Vol. 22. May 25, 2023, p. 1934. doi: 10.1001/jama.2023.8823.

C. Greene et alBlood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairmentNature Neuroscience. Published online February 22, 2024. doi:.1038/s41593-024-01576-9.

B. A. Krishna et alSpontaneous, persistent, T cell–dependent IFN-γ release in patients who progress to Long CovidScience Advances. Published online February 21, 2024. doi: 10.1126/sciadv.adi9379.

K. Baillie et alComplement dysregulation is a prevalent and therapeutically amenable feature of long COVIDMed. Published online February 14, 2024. doi: 10.1016/j.medj.2024.01.011.

C. Cervia-Hasler et alPersistent complement dysregulation with signs of thromboinflammation in active long COVID. Science. Vol. 383. January 19, 2024. doi: 10.1126/science.adg7942.

K. Yin et alLong COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2Nature Immunology. Vol. 25. January 11, 2024, p. 218. doi:10.1038/s41590-023-01724-6.

J. Klein et alDistinguishing features of long COVID identified through immune profiling. Nature. Vol. 623. September 25, 2023, p. 139. doi:10.1038/s41586-023-06651-y.

M.J. Peluso et alMultimodal molecular imaging reveals tissue-based T cell activation and viral RNA persistence for up to 2 years following COVID-19. medRxiv.org. Posted July 31, 2023. doi: 10.1101/2023.07.27.23293177.

E.R. Praff et alCoding long COVID: characterizing a new disease through an ICD-10 lens. BMC Medicine. Vol 21. February 16, 2023. doi: 10.1186/s12916-023-02737-6.

H.E. Davis et alLong COVID: major findings, mechanisms and recommendationsNature Reviews Microbiology. Vol 21. January 13, 2023, p. 133. doi: 10.1038/s41579-022-00846-2. 

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